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Colchicine tablets sale and purchase is being restricted to authorised health professionals only. The National Health Service (NHS) has confirmed that the medicine will no longer be available in pharmacies England after its use in children with leukemia and other cancers was brought to an end by the medicines regulator. The NHS said decision, which was made by its Medicines and Healthcare products Regulatory Agency (MHRA), had been "unanimous" due to the "lack of evidence support use the medicine in children or buy colchicine tablets young people". The NSHR (which provides guidance to NHS trusts and doctors), the MHRA British Medical Association have expressed deep concerns about its use and will be conducting a full review of its safety for NHS use. "There simply are no compelling medical reasons for the prescribing of cancer drug in children at this time," said the chair of NSHR, Dr Sarah Wollaston, a GP and former chair of the All-party Parliamentary Group on Health. "We believe that such restrictions are wrong and unnecessary." The drug was used on a case-by-case basis in children with acute lymphoblastic leukaemia and had been approved as a treatment only for adults. But there is now concern that it still plays a role in childhood leukaemia, with some experts believing it has the ability to cause a second cancer. Leukaemia is a cancer of the white blood cells and most common types can cause cancerous nodules to grow inside a patient's bone marrow. The disease is currently a major problem among children and young people, it is estimated that around one in every 100 children has it. Although it is rare, there are now serious Is propecia better than generic finasteride concerns that the drug is still used in such a way that it increases the risk of cancer developing. National Institute for Health and Care Excellence is currently assessing the role it still plays in childhood leukaemia, but there is evidence that the drugs in question can cause cancer when used on people who have already been diagnosed with it. "There is no good reason to suggest that the use of this drug should be expanded in the UK," said NSHR a statement. "There now appear to be substantial risks the health of children if these are not carefully monitored. It is now the responsibility of NHS trust commissioners and GPs to ensure that this drug is not administered for a second time in children who are already receiving treatment." The decision to allow colchicine tablet dosage drugs no longer be used in children comes after the NSHR raised concerns with Gilead over a series of reports showing its cancer drug Harvoni was being marketed and administered inconsistently. One of these reports from January showed a group of patients prescribed Harvoni, which is only effective in patients with acute non-Hodgkin lymphoma, were being administered a separate treatment that reduced the number of anti-cancer drugs being given the patient. Gilead said in a statement: "We respect the role and values of NSHR our responsibilities under their guidance, and work closely with them to improve our products, provide clear and accurate information on the products' benefits and risks to ensure that there is an appropriate balance between clinical needs of Best drugstore contour powder uk patients and public safety. " The medicines regulator added that it was concerned the number of colchicine tablets dosage gout patients being prescribed the cancer drug was growing out of balance, and "it does not appear acceptable that these are the results of this growth".

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